Equipment and Facilities – University of Copenhagen

Forward this page to a friend Resize Print Bookmark and Share

Panum NMR Core Facility > Equipment and Facilities

Equipment and Facilities

The Bruker 9.4T NMR instrument was acquired 2012-13 and placed in a new NMR lab in the basement of Building 23. The instrument was acquired with funds from the 'National Program for Research Infrastructure', while the Faculty (SUND-KU) financed refurbishment of the 23-01 lab. The 9.4T scanner was fully operational in February 2014, with a wide range of unique accessories, including two advanced cryoprobes (1H and 31P), and a range of coils for both 1H and X-nuclei imaging and spectroscopy.

Bruker Biospec 9.4/30 USR AVANCEIII/MRI, 400MHz Spectrometer

The Bruker BioSpec 94/30 USR is a 9.4 Tesla NMR instrument with a 30 cm bore. It is equipped with a range of gradients (20cm, 100mT/m; 12cm, 240mT/m; and 6cm 1500mT/m), and coils, including both 1H and 31P cryoprobes, 1H volume coils ranging from 2.3 to 15.4 cm, quadrature 1H array coils for mouse and rat brain and heart, and surface coils for 6Li, 13C, 15N, 19F, 23Na, and 31P. The scanner can be controlled by either ParaVision 5.1 or 6.01 for MRI/MRS acquisition, and the facility includes a powerful post-processing computer.

Animal preparation and physiological monitoring

The NMR facility has an animal preparation room with a surgical setup including: surgical microscope, stereotaxic frame, heater pad, surgical tools, and a separate isoflurane anesthesia setup for induction and surgery.

The facility is equipped with an MR-safe animal physiological monitoring system from SA instruments for recording pulse-oximetry (heart rate, O2 saturation), respiration rate, and temperature during scanning. Water heated beds and tubes are available for maintaining body temperature, and the scanner is equipped with an isoflurane delivery system.

Workshop

The workshop offers technical support and advice in the MRS/MRI prototype development. This includes:

  • Guidance on the selection of experiment, help in setting up experiments, guidance and training of researchers and laboratory staff in carrying out experiments etc.
  • Development and construction of experimental prototypes and equipment for new experiments, including: mechanical prototype development and construction, in the form of metal and plastic machining as turning, milling, drilling, etc., and, 3D printing.
  • Electronic prototype development and construction of any kind from DC to 3GHz, including custom MRS/MRI probes.