Equipment and Facilities
The Bruker 9.4T NMR instrument was acquired 2012-13 and placed in a new NMR lab in the basement of Building 23 (23.01). The instrument was acquired with funds from the 'National Program for Research Infrastructure', while the Faculty (SUND-KU) financed refurbishment of the 23-01 lab. The 9.4T scanner was fully operational in February 2014, with a wide range of unique accessories, including two advanced cryoprobes (1H and 31P), and a range of coils for both 1H and X-nuclei imaging and spectroscopy.
Bruker Biospec 9.4/30 USR AVANCEIII/MRI
- 9.4 Tesla (400MHz) Spectrometer
- 30 cm holizontal bore
- Active shealded
|100mT/m||20cm, Max Current = 300A|
|240mT/m||12cm, Max Current = 300A|
|1500mT/m||6cm, Max Current = 200A|
|400MHz 1H CryoProbe||Mouse brain quadrature surface coil Tx/Rx|
|162MHz 31P CryoProbe||For high-sensitive ATP / pH analysis|
Ordinary Room-temperature Coils
|Double-tuned Surface Coils||
|Single-tuned Surface Coils||
13C/23Na/31P 100-162MHz iD20mm
15N/6Li/2N 40-62MHz iD20mm
1H Rat Heart Array
1H Rat Brain Array
1H Mouse Heart Array
1H Mouse Brain Array
1H Planar Surface iD10mm
1H Rabbit Body iD154mm
1H Rat Body iD86mm
1H Rat Head/Mouse Body iD40mm
1H Mouse Body iD35mm
1H Mouse Head iD23mm
Softwares and Computers
- ParaVision 5.1 or 6.01 for MRI/MRS acquisition
- powerful post-processing computers
Animal preparation and physiological monitoring
The NMR facility has an animal preparation room with a surgical setup including:
- surgical microscope
- stereotaxic frame
- heater pad
- surgical tools
- separate isoflurane anesthesia setup for induction and surgery.
The facility is equipped with an MR-safe animal physiological monitoring system from SA instruments for
- monitoring ECG, pulse-oximetry (heart rate, O2 saturation), respiration rate, and temperature during scanning.
- Water heated beds and tubes are available for maintaining body temperature
- Isoflurane / Air / O2 / N2 delivery system.
The workshop offers technical support and advice in the MRS/MRI prototype development. This includes:
- Guidance on the selection of experiment, help in setting up experiments, guidance and training of researchers and laboratory staff in carrying out experiments etc.
- Development and construction of experimental prototypes and equipment for new experiments, including: mechanical prototype development and construction, in the form of metal and plastic machining as turning, milling, drilling, etc., and, 3D printing.
- Electronic prototype development and construction of any kind from DC to 3GHz, including custom MRS/MRI probes.